TargetKinesin-like protein KIF11(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MT-stimulated ATPase activity of wild type Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-diprenorphine binding to kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]-diprenorphine binding to kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration of the compound against Thrombin was determinedMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligandMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Effective concentration against retinoic acid receptor alpha in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (4.6-8.9)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]-diprenorphine binding to kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition concentration of the compound against beta tryptase was determinedMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 227nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 253nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligandMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 329nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced increase in Ca2+ level pretreated for...More data for this Ligand-Target Pair
Affinity DataIC50: 433nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 445nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 463nMAssay Description:Displacement of [3H]Mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 479nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Displacement of [3H]Mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 543nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
Affinity DataIC50: 555nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 625nMAssay Description:Inhibitory concentration of the compound against Factor Xa was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 702nMAssay Description:Displacement of [3H]Ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 15 minsMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 703nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 706nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 722nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced increase in Ca2+ level pretreated for...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 812nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 855nMAssay Description:Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligandMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligandMore data for this Ligand-Target Pair