Compile Data Set for Download or QSAR
maximum 50k data
Found 1150 with Last Name = 'kraus' and Initial = 'b'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468324(CHEMBL4277484)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468325(CHEMBL4292609)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468322(CHEMBL4285431)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50396135(CHEMBL2171328)
Affinity DataIC50:  2nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50396135(CHEMBL2171328)
Affinity DataIC50:  2.04nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468327(CHEMBL4291041)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377432(CHEMBL258927)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of electric eel AchE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468320(CHEMBL4292205)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of electric eel AchE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468321(CHEMBL4284297)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289025(CHEMBL164479 | N-(2,6-Diisopropyl-phenyl)-malonami...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289051(CHEMBL160103 | N-(2,6-Diisopropyl-phenyl)-malonami...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377439(CHEMBL257126)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of electric eel AchE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468317(CHEMBL4279707)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377432(CHEMBL258927)
Affinity DataIC50:  5nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051461(CHEMBL264861 | N-(2,6-Diisopropyl-phenyl)-2-(2-dod...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 of liver microsomes isolated from cholesterol-fed rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.13nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377431(CHEMBL258744)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50261344(CHEMBL466338 | N-(3-{[6-Chloro-2,3-dihydropyrrolo[...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of equine serum BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377436(CHEMBL255304)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051466(CHEMBL175982 | N-(2,6-Diisopropyl-phenyl)-2-(5-dod...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 of liver microsomes isolated from cholesterol-fed rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289024(CHEMBL422709 | N-(2,6-Diisopropyl-phenyl)-malonami...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50045906(3-Oxo-hexadecanoic acid (2,6-diisopropyl-phenyl)-a...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377439(CHEMBL257126)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006407(CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)
Affinity DataIC50:  7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006409(CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)
Affinity DataIC50:  7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50069883((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50005955(CHEMBL40608 | Octadec-9-enoic acid (2,6-diisopropy...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006407(CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)
Affinity DataIC50:  7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50069886((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377433(CHEMBL258926)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377436(CHEMBL255304)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of electric eel AchE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468326(CHEMBL4288791)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051460(2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase 1 from rabbit intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50039427(+/-(1-Methyl-Tridecyl)Thiocarbonyl-carbamic acid 2...)
Affinity DataIC50:  8nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063243(CHEMBL161499 | N-(2,6-Diisopropyl-phenyl)-2-pyridi...)
Affinity DataIC50:  8nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054305(1-(2,6-Diisopropyl-phenyl)-3-(2-undecyl-2,3-dihydr...)
Affinity DataIC50:  9nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281484(1-(2,6-Diisopropyl-phenyl)-3-(4-undecyl-phenyl)-ur...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50039428(CHEMBL77339 | Tridecyloxycarbonyl-carbamic acid 2,...)
Affinity DataIC50:  9nMAssay Description:In vitro Acyl coenzyme A:cholesterol acyltransferase inhibitory activity (IAI) was determined by measuring the incorporation of [1-14C]oleolyl-CoA in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281487(1-(2,6-Diisopropyl-phenyl)-3-(4-nonyl-phenyl)-urea...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50054300(1-(2,6-Diisopropyl-phenyl)-3-(2-tridecyl-2,3-dihyd...)
Affinity DataIC50:  9nMAssay Description:Acyl coenzyme A:cholesterol acyltransferase 1 inhibition in vitro measured in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468328(CHEMBL4281183)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50377435(CHEMBL256919)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of electric eel AchE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468318(CHEMBL4287618)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1150 total ) | Next | Last >>
Jump to: