Affinity DataKi: 4.40E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity towards mGluR1a was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 2.05E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Tested for inhibitory activity against kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory activity against Kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonistic activity against mGluR2 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1(Homo sapiens (Human))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Antagonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slicesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+5nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP formation in BHK cells expressing mGluR2.More data for this Ligand-Target Pair