TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -53.1kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
Affinity DataKi: 1.39nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.56nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research and Development
Curated by ChEMBL
Global Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair