Report error Found 184 with Last Name = 'moniz' and Initial = 'g'
Affinity DataKi: 3nM ΔG°: -48.2kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -44.8kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 12.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -44.6kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -44.6kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.4kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 17.3nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.5kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.1kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.1kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -43.0kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -42.9kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 27.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -42.7kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -42.7kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 30.6nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 32nM ΔG°: -42.3kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 34nM ΔG°: -42.2kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -41.9kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 47nM ΔG°: -41.4kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 47.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 55nM ΔG°: -41.0kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nM ΔG°: -40.9kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 64nM ΔG°: -40.6kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 73nM ΔG°: -40.3kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 82nM ΔG°: -40.0kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -39.1kJ/molepH: 7.2 T: 22°CAssay Description:Enzyme assays were performed using purified recombinant enzymes, incubating with test compound and [3H]cortisone/NADPH. After incubation, the amount ...More data for this Ligand-Target Pair
Affinity DataKi: 126nM ΔG°: -39.0kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 149nM ΔG°: -38.6kJ/molepH: 7.2 T: 22°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
Affinity DataKi: 180nM ΔG°: -38.1kJ/molepH: 7.2 T: 22°CAssay Description:Enzyme assays were performed using purified recombinant enzymes, incubating with test compound and [3H]cortisone/NADPH. After incubation, the amount ...More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair