Affinity DataKi: 0.0220nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0260nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Mitsubishi Tanabe Pharma
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair