Compile Data Set for Download or QSAR
maximum 50k data
Found 626 with Last Name = 'mcfarland' and Initial = 'j'
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259863(US9505766, 68)
Affinity DataIC50:  2nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259840(US9505766, 44)
Affinity DataIC50:  2.40nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259876(US9505766, 81)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259807(US9505766, CN-NH2 (6))
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259861(US9505766, 66)
Affinity DataIC50:  3.60nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259839(US9505766, 43)
Affinity DataIC50:  3.80nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM50403059(CHEMBL2216829 | US9505766, 64)
Affinity DataIC50:  4.5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259844(US9505766, 48)
Affinity DataIC50:  4.70nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259870(US9505766, 75)
Affinity DataIC50:  4.80nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259808(US9505766, 74 | US9505766, CN-NHiPr (7))
Affinity DataIC50:  5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259845(US9505766, 49)
Affinity DataIC50:  6.5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259806(US9505766, CN-OtBu (5))
Affinity DataIC50:  7nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592760(2-chloro-N-(8-cyano-8- azabicyclo[3.2.1]octan-2-yl...)
Affinity DataIC50:  10nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259858(US9505766, 62)
Affinity DataIC50:  10.5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259872(US9505766, 77)
Affinity DataIC50:  12.6nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259805(US9505766, CN-OMe (4))
Affinity DataIC50:  13nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259846(US9505766, 50)
Affinity DataIC50:  13.2nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259836(US9505766, 40)
Affinity DataIC50:  14nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259837(US9505766, 41)
Affinity DataIC50:  14nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259862(US9505766, 67)
Affinity DataIC50:  14.8nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592741((3S)-6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  17nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259867(US9505766, 72)
Affinity DataIC50:  17nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592645((3S)-6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  20nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259875(US9505766, 80)
Affinity DataIC50:  20.9nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592753(1-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  22nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259842(US9505766, 46)
Affinity DataIC50:  23.2nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259841(US9505766, 45)
Affinity DataIC50:  24.3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592951(US11572374, Example 12-2-3)
Affinity DataIC50:  25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592927((3S)-1-(3-chloro-5-methylphenyl)-N- ((1R.2R,4S)-7-...)
Affinity DataIC50:  25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592654(6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592779((3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592826(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259868(US9505766, 73)
Affinity DataIC50:  26.1nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592861(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592735(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592819(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  28nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592920((3S)-1-(3-chloro-6-(trifluoromethyl)-2- pyridinyl)...)
Affinity DataIC50:  29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592926((3S)-1-(3-chloro-5-(trifluoromethyl)phenyl)- N-((1...)
Affinity DataIC50:  29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592827(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  30nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259873(US9505766, 78)
Affinity DataIC50:  30.4nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592697(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  31nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592775((3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  34nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592924((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592755(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592781((2E)-3-(5-chloro-1-benzothiophen-3-yl)-N- ((1R,2R,...)
Affinity DataIC50:  38nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592839(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  39nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592778((2E)-3-(5-chloro-1-ethyl-1H-indol-3-yl)-N- ((1R,2R...)
Affinity DataIC50:  40nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259809(US9505766, CN-NHBn (8))
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259855(US9505766, 59)
Affinity DataIC50:  40nMT: 2°CAssay Description:Btk (human, full length) was purchased (Invitrogen, catalog number PV3363) and used as specified in the product literature. Btk (2 nM final concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259877(US9505766, 82)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 626 total ) | Next | Last >>
Jump to: