Report error Found 246 with Last Name = 'no' and Initial = 'jh'
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus (strain VF5))
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrateMore data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Illinois
University of Illinois
Affinity DataKi: 500nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus (strain VF5))
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 910nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus (strain VF5))
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrateMore data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Escherichia coli (strain K12))
University of Illinois
University of Illinois
Affinity DataKi: 3.00E+3nMAssay Description:In order to find new inhibitors, we carried out in silico screening of AaIspH and EcIspH using ZINC and National Cancer Institute (NCI) libraries and...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 4.10E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKi: 8.30E+6nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair