Affinity DataKi: 0.0120nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
Affinity DataKi: 0.0440nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
Affinity DataKi: 0.105nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In vitro inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of PI3K subunit p110alpha assessed as formation of phosphatidylinositide-3-phosphate product formation after 30 mins by fluorescence polar...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 as substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair