TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]NMS from human muscarinic acetylcholine receptor subtype 5 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: 2.34E+3nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Riken Advanced Science Institute
Curated by ChEMBL
Riken Advanced Science Institute
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+4nMAssay Description:Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0440nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0550nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0550nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0660nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0780nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0830nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0970nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.128nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as a substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMpH: 7.5Assay Description:Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...More data for this Ligand-Target Pair