Compile Data Set for Download or QSAR
maximum 50k data
Found 616 with Last Name = 'mogemark' and Initial = 'm'
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50274638(CHEMBL4126156 | US10858355, Example 4)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to human P2Y1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512885(CHEMBL4441003)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512862(CHEMBL4541570)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512880(CHEMBL4468379)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of PI3Kdelta in human SUDHL6 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512872(CHEMBL4470131)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM236918(US9388189, 1)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM489244(N-{6-[(5-{2-[(1S)-1-Cyclopropylethyl]-7-(methylsul...)
Affinity DataIC50:  0.300nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489245(N-{6-[(5-{2-[(1S)-1-Cyclopropylethyl]-7-(methylsul...)
Affinity DataIC50:  0.300nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM350391((S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM474011(N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-({[1-(fluorome...)
Affinity DataIC50:  0.398nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474007(N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-(ethylsulfamoy...)
Affinity DataIC50:  0.398nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489241(N-{6-[(5-{2-[(1S)-1-Cyclopropylethyl]-7-(methylsul...)
Affinity DataIC50:  0.400nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489251(2-[(1S)-1-Cyclopropylethyl]-6-(2-{[6-(1,1-dioxido-...)
Affinity DataIC50:  0.400nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50512875(CHEMBL4567071)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by insulin stimulation for 5 mins by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM489253(N-{6-[(5-{2-[(1S)-1-Cyclopropylethyl]-7-(ethylsulf...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489256(6-(4-Methyl-2-{[6-(2-oxo-1,3-oxazinan-3-yl)pyridin...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489257(6-(4-Methyl-2-{[6-(2-oxoimidazolidin-1-yl)pyridin-...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489261(2-[(1S)-1-Cyclopropylethyl]-6-(4-methyl-2-{[6-(2-o...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489281(2-[(1S)-1-Cyclopropylethyl]-6-[2-({6-[(3R)-3-hydro...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489283(2-[(1S)-1-Cyclopropylethyl]-6-[2-({6-[(3S)-3-hydro...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489287(6-[2-({6-[(3S)-3-Hydroxy-2-oxopyrrolidin-1-yl]pyri...)
Affinity DataIC50:  0.5nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474028(N-(5-{7-[(3-Cyanophenyl)sulfamoyl]-2-[(1S)-1-cyclo...)
Affinity DataIC50:  0.501nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489281(2-[(1S)-1-Cyclopropylethyl]-6-[2-({6-[(3R)-3-hydro...)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579665(CHEMBL5082066)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579666(CHEMBL5081964)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM489248(2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-(4-methyl-2...)
Affinity DataIC50:  0.600nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489264(6-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)
Affinity DataIC50:  0.600nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50512883(CHEMBL4460140)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM489237(5-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)
Affinity DataIC50:  0.600nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50579671(CHEMBL5090959)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579667(CHEMBL5090799)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50274648(CHEMBL4127396 | US10858355, Example 22)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human 6His-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50274660(CHEMBL4128537 | US10858355, Example 12)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human 6His-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50274640(CHEMBL4126445)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human 6His-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM489248(2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-(4-methyl-2...)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579668(CHEMBL5091438)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512861(CHEMBL4558527)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM489261(2-[(1S)-1-Cyclopropylethyl]-6-(4-methyl-2-{[6-(2-o...)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM489247(2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-(4-methyl-2...)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in ADP production using Dic8-PIP2 as substrate pre-treated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM474012(N-(5-{2-[(1S)-1-Cyclopropylethyl]-1-oxo-7-[(2,2,2-...)
Affinity DataIC50:  0.631nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474008(N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-(oxetan-3-ylsu...)
Affinity DataIC50:  0.631nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50274648(CHEMBL4127396 | US10858355, Example 22)
Affinity DataIC50:  0.631nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM50274638(CHEMBL4126156 | US10858355, Example 4)
Affinity DataIC50:  0.631nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM474015(N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-[(cyclopropyls...)
Affinity DataIC50:  0.631nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489247(2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-(4-methyl-2...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489252(N-Methyl-6-(4-methyl-2-{[6-(2-oxopyrrolidin-1-yl)p...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489254(N-Ethyl-6-(4-methyl-2-{[6-(3-oxomorpholin-4-yl)pyr...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489259(2-[(1S)-1-Cyclopropylethyl]-6-(4-methyl-2-{[6-(2-o...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489275(2-[(1S)-1-Cyclopropylethyl]-6-(2-{[6-(5,5-dimethyl...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM489280(2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-(4-methyl-2...)
Affinity DataIC50:  0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 616 total ) | Next | Last >>
Jump to: