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TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataKi:  0.00800nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataKi:  0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to the Endothelin A receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287890(CHEMBL427778 | Suc-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu...)
Affinity DataKi:  0.0770nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287885(CHEMBL405377 | Suc-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu...)
Affinity DataKi:  0.25nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50036402(CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50036402(CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274809(3,5-Diiodo-4-(4'-hydroxy-3'-isopropylphenoxy)benzy...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287883(CHEMBL412003 | Suc-Glu-Ala-Gly-Tyr-Phe-Ala-His-Leu...)
Affinity DataKi:  0.910nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274812(CHEMBL457528 | [3,5-Diiodo-4-(4'-hydroxy-3'-isopro...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287882(CHEMBL412065 | Suc-Glu-Ala-Val-Tyr-Phe-Ala-Gly-Leu...)
Affinity DataKi:  1nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50071433((S)-2-{(R)-3-Biphenyl-4-yl-2-[(3,5-dimethyl-benzoy...)
Affinity DataKi:  1nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKi:  1.09nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274846(CHEMBL511862 | [3,5-Dibromo-4-(4'-hydroxy-3'-isopr...)
Affinity DataKi:  1.51nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274809(3,5-Diiodo-4-(4'-hydroxy-3'-isopropylphenoxy)benzy...)
Affinity DataKi:  1.84nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  2.17nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275295(2-[3,5-Dibromo-4-(4'-hydroxy-3'-isopropylphenoxy)p...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274811(CHEMBL457527 | [3,5-Dibromo-4-(4'-hydroxy-3'-isopr...)
Affinity DataKi:  2.51nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  2.95nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274812(CHEMBL457528 | [3,5-Diiodo-4-(4'-hydroxy-3'-isopro...)
Affinity DataKi:  3.74nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287878(CGP-49941 | CHEMBL305615 | N-{(R)-1-[2-(1H-Indol-3...)
Affinity DataKi:  5nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287888(CHEMBL407559 | Suc-Glu-Ala-Val-Tyr-Phe-Gly-His-Leu...)
Affinity DataKi:  5.30nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287886(CHEMBL405796 | Suc-Glu-Ala-Val-Tyr-Phe-Ala-His-Gly...)
Affinity DataKi:  5.90nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275257(CHEMBL448595 | [3,5-Dimethyl-4-(3'-sec-butyl-4'-hy...)
Affinity DataKi:  6.64nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  7.18nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  7.79nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275291(CHEMBL485758 | [4-(4'-Hydroxy-3'-isopropylbenzyl)-...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275228(CHEMBL485928 | [3,5-Dimethyl-4-(3'-ethyl-4'-hydrox...)
Affinity DataKi:  9.72nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274846(CHEMBL511862 | [3,5-Dibromo-4-(4'-hydroxy-3'-isopr...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287887(CHEMBL413604 | Suc-Glu-Ala-Val-Gly-Phe-Ala-His-Leu...)
Affinity DataKi:  11nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275294(CHEMBL519721 | [3,5-Dibromo-4-(4'-hydroxy-3'-isopr...)
Affinity DataKi:  15.5nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287880((S)-3-(1H-Indol-3-yl)-2-[(2-phenyl-cyclopropanecar...)
Affinity DataKi:  16nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274810(3,5-Diiodo-4-(4'-hydroxy-3'-iodophenoxy)benzylphos...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274811(CHEMBL457527 | [3,5-Dibromo-4-(4'-hydroxy-3'-isopr...)
Affinity DataKi:  18.6nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274813(CHEMBL457529 | [3,5-Dimethyl-4-(4'-hydroxy-3'-isop...)
Affinity DataKi:  25.4nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274810(3,5-Diiodo-4-(4'-hydroxy-3'-iodophenoxy)benzylphos...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275291(CHEMBL485758 | [4-(4'-Hydroxy-3'-isopropylbenzyl)-...)
Affinity DataKi:  28.4nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275257(CHEMBL448595 | [3,5-Dimethyl-4-(3'-sec-butyl-4'-hy...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274814(CHEMBL516330 | [3,5-Dichloro-4-(4'-hydroxy-3'-isop...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275290(2-[3,5-Dimethoxy-4-(4'-hydroxy-3'-isopropylbenzyl)...)
Affinity DataKi:  31.3nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  35.2nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  35.2nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50275226(CHEMBL505084 | N-[3,5-Dimethyl-4-(3'-isopropyl-4'-...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50071431((S)-2-{(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]...)
Affinity DataKi:  36nMAssay Description:Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
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