TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in human K177 cell membrane incubated for 75 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in human K177 cell membrane incubated for 75 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Binding affinity to human alpha3beta4 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]nicotine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in human K177 cell membrane incubated for 75 mins by liquid scintillation spectro...More data for this Ligand-Target Pair
Affinity DataKi: 1.02nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 1.13nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of 3H-cytisine from Sprague-Dawley rat brain alpha4beta2 nAChR by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in K28 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.74nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Binding affinity to rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to human alpha3beta4 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of 3H-cytisine from rat brain alpha4beta2 nAChR by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat frontal cortex membrane by scintillation counting methodMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-1(Bos taurus)
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Competitive inhibition of bovine GABAA alpha1beta1 expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhbition of [3H] nicotine binding to rat brain alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity to rat alpha4beta2 nAChRMore data for this Ligand-Target Pair
Affinity DataKi: 50.7nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Binding affinity to rat alpha7 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 93.1nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Displacement of [3H]-cytisine from rat brain membrane alpha4beta2 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 119nMAssay Description:Displacement of 3H-cytisine from Sprague-Dawley rat brain alpha4beta2 nAChR by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 123nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 133nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 133nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 136nMAssay Description:Displacement of [3H]-cytisine from rat brain membrane alpha4beta2 nAChRMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 249nMAssay Description:Displacement of 3H-cytisine from Sprague-Dawley rat brain alpha4beta2 nAChR by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Inhibition of Adenosine deaminase (ADA) of calf intestineMore data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Compound was evaluated for inhibition of calf intestinal mucosa adenosine deaminase (ADA)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Displacement of 125I-alpha-bungarotoxin from rat brain alpha7 nAChR by radioligand binding assayMore data for this Ligand-Target Pair