Affinity DataKi: 2nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 139nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 146nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 208nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 303nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 438nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 792nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 875nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.01E+3nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.08E+3nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.23E+3nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.57E+3nMAssay Description:Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.355nMAssay Description:Displacement of 125I-MIP-1beta from human CCR5 receptor after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair