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Found 3 Enz. Inhib. hit(s) with Target = 'Ileal sodium/bile acid cotransporter' and Ligand = 'BDBM50434850'
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434850(CHEMBL2387397)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434850(CHEMBL2387397)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50434850(CHEMBL2387397)
Affinity DataIC50:  4nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed