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Found 36 with Last Name = 'seeram' and Initial = 'np'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238966(CHEMBL4095230)
Affinity DataIC50:  420nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238965(CHEMBL4087528)
Affinity DataIC50:  450nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238962(CHEMBL4067813)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238967(CHEMBL4086544)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238964(CHEMBL4102979)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50238963(CHEMBL4078699)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  8.90E+3nMAssay Description:In vitro inhibitory activity against hog plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50219502(4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503625(CHEMBL4442228)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503630(CHEMBL4465955)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503622(CHEMBL4514018)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50168143(CHEMBL3805523)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503620(CHEMBL4530299)
Affinity DataIC50:  1.54E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503617(CHEMBL4482921)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503627(CHEMBL4462546)
Affinity DataIC50:  1.91E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503629(CHEMBL4553753)
Affinity DataIC50:  2.12E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503628(CHEMBL4460162)
Affinity DataIC50:  2.18E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503624(CHEMBL4561682)
Affinity DataIC50:  2.44E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50168145(CHEMBL3805142)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50168144(CHEMBL3806298)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50240433(5-Isopropyl-2-methyl-phenol | CARVACROL | CHEMBL28...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503626(CHEMBL4439425)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503623(CHEMBL4578501)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503621(CHEMBL4467127)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503619(CHEMBL4476244)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503618(CHEMBL4438192)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503615(CHEMBL4573816)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503614(CHEMBL4452910)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50240432(1-hydroxy-5-methyl-2-isopropylbenzene | 2-isopropy...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503613(CHEMBL4562120)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University

Curated by ChEMBL
LigandPNGBDBM50503616(CHEMBL4450547)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50318484(2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...)
Affinity DataKd:  1.88E+5nMAssay Description:Binding affinity to recombinant human caspase-1 assessed as dissociation constant measured after 90 sec by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50318484(2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...)
Affinity DataKon:  0.0780M-1s-1Assay Description:Binding affinity to recombinant human caspase-1 assessed as dissociation constant at equilibrium measured after 30 sec by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed