TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:In vitro inhibitory activity against hog plasma reninMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 1.91E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 2.18E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: 4.70E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Susquehanna University
Curated by ChEMBL
Susquehanna University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.88E+5nMAssay Description:Binding affinity to recombinant human caspase-1 assessed as dissociation constant measured after 90 sec by SPR methodMore data for this Ligand-Target Pair
Affinity DataKon: 0.0780M-1s-1Assay Description:Binding affinity to recombinant human caspase-1 assessed as dissociation constant at equilibrium measured after 30 sec by SPR methodMore data for this Ligand-Target Pair