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Found 489 with Last Name = 'simpson' and Initial = 'p'
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093157(CHEMBL431969 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  0.100nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093175(CHEMBL311655 | Derivative of APC-2059)
Affinity DataKi:  0.100nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093192(CHEMBL311482 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  0.200nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093154(CHEMBL448786 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093156(CHEMBL432172 | Derivative of APC-2059)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093167(CHEMBL75750 | Derivative of APC-2059)
Affinity DataKi:  0.400nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093173(CHEMBL309830 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093158(1-{4-[4-amino(imino)methylaminobenzylcarbamoyl]hex...)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093199(CHEMBL75972 | Derivative of APC-2059)
Affinity DataKi:  0.5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093178(CHEMBL76883 | Derivative of APC-2059)
Affinity DataKi:  0.700nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093176(CHEMBL308763 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  1nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173700(3-Phenyl-5-(2-pyridin-4-yl-pyrimidin-4-yl)-pyridaz...)
Affinity DataKi:  1.30nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173700(3-Phenyl-5-(2-pyridin-4-yl-pyrimidin-4-yl)-pyridaz...)
Affinity DataKi:  1.60nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093186(CHEMBL76424 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  2nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093197(CHEMBL75679 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  2nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093198(CHEMBL311043 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  3nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093164(CHEMBL308632 | Derivative of APC-2059)
Affinity DataKi:  3nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173700(3-Phenyl-5-(2-pyridin-4-yl-pyrimidin-4-yl)-pyridaz...)
Affinity DataKi:  3.10nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173674(3-[6-(2-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...)
Affinity DataKi:  3.40nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  3.5nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  3.80nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093183(CHEMBL76796 | Derivative of APC-2059)
Affinity DataKi:  4nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093148(CHEMBL80930 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  4nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093161(CHEMBL308630 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  4nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173695(3-[6-(3-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...)
Affinity DataKi:  4nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093168(CHEMBL75635 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  5nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173691(3-(6-Phenyl-pyridazin-4-yl)-benzonitrile | CHEMBL1...)
Affinity DataKi:  5.20nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173683(5-(3-Bromo-phenyl)-3-ethoxy-pyridazine | CHEMBL196...)
Affinity DataKi:  5.70nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173689(3-(6-Benzylamino-pyridazin-4-yl)-benzonitrile | CH...)
Affinity DataKi:  6.10nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173691(3-(6-Phenyl-pyridazin-4-yl)-benzonitrile | CHEMBL1...)
Affinity DataKi:  7nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173695(3-[6-(3-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...)
Affinity DataKi:  7.20nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173698(CHEMBL372340 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  7.20nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  7.30nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173698(CHEMBL372340 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  7.30nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173675(5-(3-Bromo-phenyl)-3-phenyl-pyridazine | CHEMBL197...)
Affinity DataKi:  7.5nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173675(5-(3-Bromo-phenyl)-3-phenyl-pyridazine | CHEMBL197...)
Affinity DataKi:  7.90nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173674(3-[6-(2-Fluoro-phenyl)-pyridazin-4-yl]-benzonitril...)
Affinity DataKi:  7.90nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093182(CHEMBL77007 | Derivative of APC-2059)
Affinity DataKi:  8nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173682(5-(3-Isopropoxy-phenyl)-3-phenyl-pyridazine | CHEM...)
Affinity DataKi:  8.40nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173685(5-[3-(2-Methyl-2H-[1,2,4]triazol-3-ylmethoxy)-phen...)
Affinity DataKi:  8.5nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173683(5-(3-Bromo-phenyl)-3-ethoxy-pyridazine | CHEMBL196...)
Affinity DataKi:  8.60nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173685(5-[3-(2-Methyl-2H-[1,2,4]triazol-3-ylmethoxy)-phen...)
Affinity DataKi:  8.80nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093187(1,5-di{4-[4-amino(imino)methylbenzylcarbamoyl]hexa...)
Affinity DataKi:  9nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093196(CHEMBL78283 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  10nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173685(5-[3-(2-Methyl-2H-[1,2,4]triazol-3-ylmethoxy)-phen...)
Affinity DataKi:  10.4nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173677(3-(6-Phenyl-pyridazin-4-yl)-benzoic acid methyl es...)
Affinity DataKi:  11nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093190(CHEMBL308764 | Derivative of piperazine-1-carboxyl...)
Affinity DataKi:  11nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173672(3,5-Diphenyl-pyridazine-4-carboxylic acid methyl e...)
Affinity DataKi:  12nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173682(5-(3-Isopropoxy-phenyl)-3-phenyl-pyridazine | CHEM...)
Affinity DataKi:  12nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173676(3-(6-Phenyl-pyridazin-4-yl)-thiophene-2-carboxylic...)
Affinity DataKi:  12nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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