TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BSEP (unknown origin)More data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human UGT1A1More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs by...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of OATP1B3 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs by...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs by...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs b...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs by...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using fluorogenic substrate preincubated for 15 min followed by NADPH addition measured after 2 hrs...More data for this Ligand-Target Pair
Affinity DataEC50: 3.06E+3nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 182nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 135nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 425nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 282nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 318nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
Affinity DataEC50: 309nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair