Affinity DataKi: 1.20nMAssay Description:Antagonist activity at DORMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Antagonist activity at MORMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of non-lysosomal glucosylceramidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Transactivation of VDR expressed in COS7 cells assessed as reduction in 1,25-dihydroxyvitamin D3-induced transcriptional activity by transient transc...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 235nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 278nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 292nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 296nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 371nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 381nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 415nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 449nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 463nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-Lipoxygenase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 602nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 636nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 819nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 837nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 926nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 994nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair