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Found 63 with Last Name = 'codd' and Initial = 'r'
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50083164((S)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at DORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50323341(CHEMBL1209039)
Affinity DataKi:  8nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50396058(CHEMBL2170198)
Affinity DataKi:  10nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  13nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50083164((S)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  86nMAssay Description:Antagonist activity at MORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  2nMAssay Description:Inhibition of non-lysosomal glucosylceramidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50396056(CHEMBL2170202)
Affinity DataIC50:  3nMAssay Description:Transactivation of VDR expressed in COS7 cells assessed as reduction in 1,25-dihydroxyvitamin D3-induced transcriptional activity by transient transc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  11nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  22nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  110nMAssay Description:Inhibition of HDAC1 by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  136nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  189nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50:  195nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50:  235nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50:  258nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50:  278nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50:  292nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50:  296nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522142(CHEMBL566831)
Affinity DataIC50:  370nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50:  371nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50:  381nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50:  415nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50:  420nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50:  449nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50:  463nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-Lipoxygenase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50:  602nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50:  636nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522147(CHEMBL4573804)
Affinity DataIC50:  819nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50:  837nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522146(CHEMBL4469317)
Affinity DataIC50:  926nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522149(CHEMBL4516302)
Affinity DataIC50:  950nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522151(CHEMBL4571280)
Affinity DataIC50:  994nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522150(CHEMBL4466520)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522143(CHEMBL4518387)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522148(CHEMBL4454331)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522145(CHEMBL4463774)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50328678(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataIC50:  1.82E+3nMAssay Description:A FLUOR DE LYS fluorometric activity assay kit (HDAC source: HeLa cell nuclear extract) and a FLUOR DE LYS HDAC1 fluorometric drug discovery assay ki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLipoxygenase(Solanum tuberosum (potato))
The University of Sydney

LigandPNGBDBM22334(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)
Affinity DataIC50:  1.71E+4nMAssay Description:A colorimetric 5-LO assay kit (Lipoxygenase Inhibitor Screening Assay Kit) and potato 5-LO isolate were purchased from Cayman Chemicals (Ann Arbor, M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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