TargetD(1B) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Competitive binding affinity to human D5R in transfected cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Competitive binding affinity to human D3R in transfected cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Competitive binding affinity to human D2R in transfected cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Competitive binding affinity to human D4R in transfected cellsMore data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Binding affinity to fluorescent-labeled BH3 peptide from GST tagged MCL1 (172 to 320 residues) (unknown origin) expressed in Escherichia coli BL21 (D...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of fluorescein tagged Bak BH3 peptide from MCL-1 (172 to 327 residues) (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human his 6- trx tagged MCL1-Bim BH3 peptide by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as substrate by incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as substrate by incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha/P300 interaction (unknown origin) incubated for 30 mins for fluorescence anisotropy competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Antagonist activity at human his 6- trx tagged MCL1-Bim BH3 peptide by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of FITC-labeled BH3 peptide binding to MCL1 (unknown origin)More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.59E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Affinity DataKd: 1.56E+5nMAssay Description:Binding affinity to human serum albumin at 5 uM incubated for 12 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 3.02E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 2.17E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.31E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.26E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 4.93E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Affinity DataKd: 68nMAssay Description:Inhibition of alpha-Synuclein (unknown origin)More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 2.18E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to amyloid beta 40 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:Binding affinity to amyloid beta 42 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to c-MYC (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.85E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.08E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 1.27E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair