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Found 33 with Last Name = 'algar' and Initial = 's'
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592919(CHEMBL5187578)
Affinity DataKi:  5.5nMAssay Description:Competitive binding affinity to human D5R in transfected cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592919(CHEMBL5187578)
Affinity DataKi:  5.5nMAssay Description:Competitive binding affinity to human D3R in transfected cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592919(CHEMBL5187578)
Affinity DataKi:  5.5nMAssay Description:Competitive binding affinity to human D2R in transfected cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592919(CHEMBL5187578)
Affinity DataKi:  5.5nMAssay Description:Competitive binding affinity to human D4R in transfected cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610480(CHEMBL5288110)
Affinity DataKi:  530nMAssay Description:Binding affinity to fluorescent-labeled BH3 peptide from GST tagged MCL1 (172 to 320 residues) (unknown origin) expressed in Escherichia coli BL21 (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610485(CHEMBL5276552)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610484(CHEMBL5281638)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610494(CHEMBL5275844)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of fluorescein tagged Bak BH3 peptide from MCL-1 (172 to 327 residues) (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610483(CHEMBL5275323)
Affinity DataKi:  9.30E+3nMAssay Description:Displacement of fluorescent-labeled BH3 peptide from recombinant MCL1 (unknown origin) by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610492(CHEMBL5284772)
Affinity DataIC50:  3.20E+3nMAssay Description:Antagonist activity at human his 6- trx tagged MCL1-Bim BH3 peptide by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50610481(CHEMBL5282364)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as substrate by incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetIslet amyloid polypeptide(Homo sapiens)TBA
LigandPNGBDBM50610487(CHEMBL5272189)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of islet amyloid polypeptide (unknown origin) aggregationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTrypanothione reductase(Leishmania infantum)TBA
LigandPNGBDBM50610482(CHEMBL5284189)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as substrate by incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610491(CHEMBL5272424)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha/P300 interaction (unknown origin) incubated for 30 mins for fluorescence anisotropy competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610492(CHEMBL5284772)
Affinity DataIC50:  3.20E+4nMAssay Description:Antagonist activity at human his 6- trx tagged MCL1-Bim BH3 peptide by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50610493(CHEMBL5290707)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of FITC-labeled BH3 peptide binding to MCL1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592930(CHEMBL5204914)
Affinity DataEC50:  1.59E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlbumin(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592929(CHEMBL5172089)
Affinity DataKd:  1.56E+5nMAssay Description:Binding affinity to human serum albumin at 5 uM incubated for 12 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592928(CHEMBL5187471)
Affinity DataEC50:  3.02E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592927(CHEMBL5176312)
Affinity DataEC50:  2.17E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592926(CHEMBL5178743)
Affinity DataEC50:  1.31E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592925(CHEMBL5187937)
Affinity DataEC50:  1.26E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592924(CHEMBL5201584)
Affinity DataEC50:  4.93E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-synuclein(Homo sapiens (Human))TBA
LigandPNGBDBM50610486(CHEMBL5290387)
Affinity DataKd:  68nMAssay Description:Inhibition of alpha-Synuclein (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592923(CHEMBL5193714)
Affinity DataEC50:  2.18E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50610488(CHEMBL5272304)
Affinity DataKd:  700nMAssay Description:Binding affinity to amyloid beta 40 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50610489(CHEMBL5285116)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to amyloid beta 42 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMyc proto-oncogene protein(Homo sapiens)TBA
LigandPNGBDBM50610490(CHEMBL5286777)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to c-MYC (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592922(CHEMBL5209228)
Affinity DataEC50:  1.85E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592921(CHEMBL5204559)
Affinity DataEC50:  1.08E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592920(CHEMBL5193924)
Affinity DataEC50:  2.30E+3nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592919(CHEMBL5187578)
Affinity DataEC50:  1.27E+4nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50592929(CHEMBL5172089)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human D1R expressed in SK-N-MC cells assessed as inhibition of DA-induced cAMP production pretreated with compound ...More data for this Ligand-Target Pair
In DepthDetails PubMed