Report error Found 415 with Last Name = 'hameed' and Initial = 's'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: <0.5nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.600nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.600nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 0.700nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1.20nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 1.30nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 2nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca India
Curated by ChEMBL
Astrazeneca India
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 4nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 5nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 6nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 7nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 7nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 8nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 9nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 10nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 10nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 11nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramate--L-alanine ligase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Astrazeneca India
Astrazeneca India
Affinity DataIC50: 13nMT: 25°CAssay Description:The reactions (50 μL) were carried out in 50 mM Tris-HCl pH 8.0, 20 mM ammonium sulfate, 2.5 mM DTT, 0.002% Brij-35, 1 mM MgCl2, 18 μM UNAM...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMT: 25°CAssay Description:The reactions (25 μL) were carried out in 25 mM Tris-HCl pH 8.0, 10 mM ammonium sulfate, 1.25 mM DTT, 0.002% Brij-35, 10 mM MgCl2, 40 μM UN...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair