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Found 142 with Last Name = 'lindeman' and Initial = 's'
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50080960(2-Bromo-N-[(1S,2S)-3-{[2-(2,4-dichloro-phenyl)-eth...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  0.0953nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused VDR (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed as beta-lac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM398047(US10322118, Entry 5)
Affinity DataIC50:  0.103nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused TRbeta receptor (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.107nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused ERalpha (unknown origin) ligand binding domain expressed in UAS-bla GripTite 293 cells assessed as ...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM18660((10S,11S,14S,15S)-14,15-dimethyl-14-propanoyltetra...)
Affinity DataIC50:  0.236nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused PR (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed as beta-lact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of fluorescent labeled 17beta-estradiol from human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  0.302nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused androgen receptor (unknown origin) ligand binding domain expressed in UAS-bla GripTite 293 cells as...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataIC50:  0.305nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused MR (unknown origin) ligand binding domain expressed in UAS-bla H cells assessed as beta-lactamase t...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.579nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused ERbeta (unknown origin) ligand binding domain expressed in UAS-bla GripTite 293 cells assessed as b...More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50: <1nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589452(CHEMBL5184751)
Affinity DataIC50:  1.30nMAssay Description:Displacement of fluorescent labeled 17beta-estradiol from human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of coactivator binding to human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  2.40nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused GR (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed as beta-lact...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589454(CHEMBL5186437)
Affinity DataIC50:  4.40nMAssay Description:Displacement of fluorescent labeled 17beta-estradiol from human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin E(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50: <7.5nMAssay Description:Inhibition of cathepsin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055925(CHEMBL3321939 | US9884814, Compound 99)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
Affinity DataIC50:  13nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused PPARdelta receptor (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells asses...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589454(CHEMBL5186437)
Affinity DataIC50:  20nMAssay Description:Inhibition of coactivator binding to human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055892(CHEMBL3321931 | US9884814, Compound 44)
Affinity DataIC50:  24nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055931(CHEMBL3321933 | US9884814, Compound 272)
Affinity DataIC50:  44nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055908(CHEMBL3321925 | US9884814, Compound 141)
Affinity DataIC50:  58nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055934(CHEMBL3321927 | US9884814, Compound 51)
Affinity DataIC50:  67nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055930(CHEMBL3321934 | US9884814, Compound 276)
Affinity DataIC50:  81nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589452(CHEMBL5184751)
Affinity DataIC50:  83nMAssay Description:Inhibition of coactivator binding to human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50080960(2-Bromo-N-[(1S,2S)-3-{[2-(2,4-dichloro-phenyl)-eth...)
Affinity DataIC50:  85nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055932(CHEMBL3321932 | US9884814, Compound 212)
Affinity DataIC50:  92nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055893(CHEMBL3321929)
Affinity DataIC50:  98nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055936(CHEMBL3321926 | US9884814, Compound 25)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055924(CHEMBL3321940 | US9884814, Compound 270)
Affinity DataIC50:  140nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055907(CHEMBL3321928 | US9884814, Compound 60)
Affinity DataIC50:  170nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055933(CHEMBL3321930)
Affinity DataIC50:  170nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50:  210nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055923(CHEMBL3321941 | US9884814, Compound 269)
Affinity DataIC50:  240nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50080973(3,5-Dichloro-2-(3,5-dichloro-2-hydroxy-benzenesulf...)
Affinity DataIC50:  250nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055928(CHEMBL3321936)
Affinity DataIC50:  280nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055910(CHEMBL3321923 | US9884814, Compound 13)
Affinity DataIC50:  320nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Merck

Curated by ChEMBL
LigandPNGBDBM50055908(CHEMBL3321925 | US9884814, Compound 141)
Affinity DataIC50:  330nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055929(CHEMBL3321935 | US9884814, Compound 200)
Affinity DataIC50:  370nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055922(CHEMBL3321913)
Affinity DataIC50:  440nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Merck

Curated by ChEMBL
LigandPNGBDBM50055907(CHEMBL3321928 | US9884814, Compound 60)
Affinity DataIC50:  500nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055927(CHEMBL3321937 | US9884814, Compound 273)
Affinity DataIC50:  510nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Merck

Curated by ChEMBL
LigandPNGBDBM50055892(CHEMBL3321931 | US9884814, Compound 44)
Affinity DataIC50:  620nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055926(CHEMBL3321938 | US9884814, Compound 277)
Affinity DataIC50:  690nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Merck

Curated by ChEMBL
LigandPNGBDBM50055925(CHEMBL3321939 | US9884814, Compound 99)
Affinity DataIC50:  900nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055921(CHEMBL3321914)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589453(CHEMBL5187139)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of coactivator binding to human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Bos taurus)
Merck

Curated by ChEMBL
LigandPNGBDBM50055931(CHEMBL3321933 | US9884814, Compound 272)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of cathepsin D in bovine cartilage explants assessed as reduction in sulphated GAGs level after 3 days by spectrophotometric 1,9-dimethylm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055920(CHEMBL3321915)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50589453(CHEMBL5187139)
Affinity DataIC50:  2.22E+3nMAssay Description:Displacement of fluorescent labeled 17beta-estradiol from human ERbeta ligand binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50055918(CHEMBL3321916)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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