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Found 50 with Last Name = 'fujita' and Initial = 't'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  1.13nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  1.89nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209307((S)-N-((S)-1-((S)-1-amino-1-oxo-3-(perfluorophenyl...)
Affinity DataIC50:  2.74nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  3.46nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209302((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  11.7nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209304((S)-N-((S)-1-((S)-1-amino-1-oxohexan-2-ylamino)-1-...)
Affinity DataIC50:  33.9nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209308((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209299((S)-N-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-ox...)
Affinity DataIC50:  62.2nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209301((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50:  76.5nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209300((S)-N-((S)-1-((S)-1-amino-1-oxopropan-2-ylamino)-1...)
Affinity DataIC50:  85.4nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50166048((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  87.1nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209314((S)-N-((S)-1-((S)-1-amino-3-(1H-imidazol-4-yl)-1-o...)
Affinity DataIC50:  138nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209298((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  148nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080264(1N-[21-benzyl-29-[(Z)-ethylidene]-13,14,23-trihydr...)
Affinity DataIC50:  180nMAssay Description:Evaluated for the inhibition of Human Leukocyte Elastase (HLE) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209316((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209311((S)-6-amino-5-((S)-2-((S)-1-((S)-2-amino-3-(4-hydr...)
Affinity DataIC50:  408nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  727nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209305((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50:  917nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209309((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  926nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209315((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50240512(7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209303((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  2.65E+3nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209298((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  3.15E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  3.58E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209313((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  3.81E+3nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209306((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  4.49E+3nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209315((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  5.72E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50320332(8-(3-methylbut-2-enyl)-2H-chromen-2-one | CHEMBL10...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209307((S)-N-((S)-1-((S)-1-amino-1-oxo-3-(perfluorophenyl...)
Affinity DataIC50:  8.04E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  1.03E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209305((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50:  1.14E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209302((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  1.17E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209316((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  1.52E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50303499(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50320333(7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one ...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExportin-1(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209299((S)-N-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-ox...)
Affinity DataIC50:  5.45E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209314((S)-N-((S)-1-((S)-1-amino-3-(1H-imidazol-4-yl)-1-o...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209306((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209309((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209308((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209310((S)-6-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209303((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209301((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50209304((S)-N-((S)-1-((S)-1-amino-1-oxohexan-2-ylamino)-1-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50166048((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587448(CHEMBL5087962)
Affinity DataEC50:  9.90E+4nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50031414(1-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587449(CHEMBL5081145)
Affinity DataEC50:  8.90E+3nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587450(CHEMBL5088108)
Affinity DataEC50:  5.00E+4nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed