Report error Found 758 with Last Name = 'raynham' and Initial = 't'
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of human recombinant AKR1C2 expressed in Escherichia coli BL21(DE3) using phenanthrenequinone as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+4nMAssay Description:Inhibition of human recombinant AKR1C4 expressed in Escherichia coli BL21(DE3) using phenanthrenequinone as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+5nMAssay Description:Inhibition of human recombinant AKR1C1 expressed in Escherichia coli BL21(DE3) using phenanthrenequinone as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.62E+5nMAssay Description:Inhibition of human recombinant AKR1C3 expressed in Escherichia coli BL21(DE3) using phenanthrenequinone as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells assessed as formation of PR-104H from PR-104A preincubated for 2 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against delta receptor of (endomorphin 2) in mouse vas deferens was determinedMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells assessed as formation of PR-104H from PR-104A preincubated for 2 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) overexpressed in human HCT116 cells assessed as inhibition of aerobic reduction of dinitrobenzamide...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Roche Discovery Welwyn
Curated by ChEMBL
Roche Discovery Welwyn
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration of the compound against Hepatitis C virus NS3 proteinaseMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) cells using 8-Acetyl-2,3,5,6-tetrahydro-1H,4H-1...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of AKR1C3 overexpressed in human HCT116 cells assessed as inhibition of PR-104A conversion to hydroxylamine after 2 hrs by spectrophotomet...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells assessed as formation of PR-104H from PR-104A preincubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of AKR1C3 overexpressed in human HCT116 cells assessed as inhibition of PR-104A conversion to hydroxylamine after 2 hrs by spectrophotomet...More data for this Ligand-Target Pair