Found 4 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50200622'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as substrate incubated for 2 hrs using ADHP fluorogenic peroxidase...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of ATX in human plasma assessed as decrease in hydrolysis of lysophosphatidylcholine by measuring choline release after 24 hrs by horserad...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of ATX in human plasma assessed as decrease in LPA C18:1 levels after 24 hrs by horseradish peroxidase/choline oxidase-coupled assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Babraham Research Campus
Curated by ChEMBL
Babraham Research Campus
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Inhibition of human recombinant ATX/LPC 18:1-mediated mouse 4T1 cell migration after overnight incubation by Transwell assayMore data for this Ligand-Target Pair