Report error Found 1495 with Last Name = 'long' and Initial = 'y'
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Compound was tested for inhibition of Sunflower beta-trypsinMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -57.6kJ/mole EC50: 5.10nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
3D Structure (crystal)TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: <0.300nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -56.5kJ/mole EC50: 5.70nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: <0.300nMAssay Description:Inhibition of FLT3 F594_R595insR mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: <0.300nMAssay Description:Inhibition of FLT3 R595_E596insEY mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Human)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 0.920nMAssay Description:Compound was tested for inhibition of Matriptase from human breast cancer cellsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Compound was tested for inhibition of bovine beta trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -53.0kJ/mole EC50: 6.40nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nM ΔG°: -52.4kJ/mole EC50: 7.10nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -52.2kJ/mole EC50: 1.40nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR2More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nM EC50: 2.70nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of bound [3H]-diprenorphine in cloned rat Opioid receptor kappa 1 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -49.9kJ/mole EC50: 3.5nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 4nM EC50: 1.90nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human GSKbeta H350L mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nM EC50: 10nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nM ΔG°: -49.5kJ/mole EC50: 0.200nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nM EC50: 3.90nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of bound [3H]-diprenorphine in cloned rat Opioid receptor kappa 1 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nM ΔG°: -48.9kJ/mole EC50: 0.300nMpH: 7.4 T: 37°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nM EC50: 3.80nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]DHT from human Androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
