TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in monkey (ch...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to LHRH receptor in monkey (chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid (AA) release from CHO cells expressing human Leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to monkey Leutinizing releasing hormone receptor in clo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in monkey (ch...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in rat anteri...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in rat anteri...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase-mediated 3'-end processing activityMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University of Manchester
Curated by ChEMBL
University of Manchester
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries
Curated by ChEMBL
Takeda Chemical Industries
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
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