Affinity DataKi: 1.40nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.42nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.42nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 5.54nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 5.54nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 6.42nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]diprenorphine from human kappa receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 7.70nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 8.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 9nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 9nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 9.90nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-rosiglitazone from GST-tagged PPARgammaLBD (unknown origin) after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 10.6nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 10.6nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 10.7nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair