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Found 3 Enz. Inhib. hit(s) with Target = 'Opioid growth factor receptor-like protein 1' and Ligand = 'BDBM97712'
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataKi:  9nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataKi:  9nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97712(US8476271, 18 | US8846929, 358 | US9145408, 358)
Affinity DataEC50:  62.6nMpH: 7.4 T: 2°CAssay Description:ORL-1 Receptor [35S]GTPγS Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (...More data for this Ligand-Target Pair
In DepthDetails US Patent