TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells using Rb prot...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of NADH-Fumarate reductase in Ascaris suum muscle sub-mitochondrial particles using disodium fumarate as substrate in presence of NADH aft...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4 (M1 to A326 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells using Rb prot...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK8 (unknown origin) assessed as inhibition rateMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK8 (unknown origin) assessed as inhibition rateMore data for this Ligand-Target Pair