Compile Data Set for Download or QSAR
maximum 50k data
Found 646 with Last Name = 'aoki' and Initial = 't'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  7.44nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  7.99nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  15.1nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262557((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  23.2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  27nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  30.4nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50244419((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Affinity DataKi:  60.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261726((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261791((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  670nMAssay Description:Binding affinity to adenosine 2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL2111553 | CHEMBL291536 | SB-334867)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to 5HT2c receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.29E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.34E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50261727((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50245093((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi: >3.67E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262499((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50262556((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Affinity DataKi:  4.65E+3nMAssay Description:Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445769(CHEMBL3104615)
Affinity DataIC50:  0.125nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441467(CHEMBL2436573)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441476(CHEMBL2436575)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441481(CHEMBL2436579)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441474(CHEMBL2436563)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441483(CHEMBL2436591)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441469(CHEMBL2436586)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441470(CHEMBL2436574)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445752(CHEMBL3104441)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441472(CHEMBL2436578)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441486(CHEMBL2436593)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441482(CHEMBL2436577)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441468(CHEMBL2436564)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445751(CHEMBL3104442)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441484(CHEMBL2436587)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441492(CHEMBL2436580)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445760(CHEMBL3104432)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445758(CHEMBL3104435)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445753(CHEMBL3104440)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441479(CHEMBL2436590)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441475(CHEMBL2436589)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441478(CHEMBL2436584)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445770(CHEMBL3104444)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441471(CHEMBL2436572)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445750(CHEMBL3104443)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260997(CHEMBL4073607)
Affinity DataIC50:  0.767nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543836(CHEMBL4637711)
Affinity DataIC50:  0.784nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50445763(CHEMBL3104622)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenylox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 646 total ) | Next | Last >>
Jump to: