Affinity DataKi: 96nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 12.8nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 12.8nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 26.5nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 26.5nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 34.5nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 34.5nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 37.8nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 37.8nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair