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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM234969'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

US Patent
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed