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Found 45 with Last Name = 'arif' and Initial = 'j'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591802(CHEMBL5187675)
Affinity DataIC50: <1nMAssay Description:Inhibition of HIV-1 reverse transcriptase preincubated for 45 mins followed by substrate addition by immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591798(CHEMBL3342990)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase by Picogreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591800(CHEMBL5191400)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of HIV-1 reverse transcriptase using ABTS as substrate and RNA template primed with oligo(dT)12-18 in presence of digoxigenin/biotin-label...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591803(CHEMBL5197402)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591804(CHEMBL5199273)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50181473(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50316573(6-((4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-...)
Affinity DataIC50:  275nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591801(CHEMBL5207632)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV-1 reverse transcriptase preincubated for 45 mins followed by substrate addition by immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591799(CHEMBL5188770)
Affinity DataIC50:  720nMAssay Description:Inhibition of HIV-1 reverse transcriptase using ABTS as substrate and RNA template primed with oligo(dT)12-18 in presence of digoxigenin/biotin-label...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50316571(4-(4-chlorophenyl)-6-((4-chlorophenyl)(methoxy)(1-...)
Affinity DataIC50:  923nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591805(CHEMBL5198501)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50316572(4-(4-Fluorophenyl)-6-((4-chlorophenyl)(methoxy)(1-...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50316570(4-(phenyl)-6-((4-chlorophenyl)(methoxy)(1-methyl-1...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50370385((R)-TIPIFARNIB | R-11577 | R-115777 | Tipifarnib |...)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591796(CHEMBL5189624)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of recombinant HIV-1 subtype C integrase using double-stranded FITC-labelled target DNA as substrate pre-incubated for 45 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591797(CHEBI:2822 | CHEMBL505516)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of recombinant HIV-1 subtype C integrase using double-stranded FITC-labelled target DNA as substrate pre-incubated for 45 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  7.41E+4nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase using ABTS as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591795((-)-Quinic Acid | CHEBI:36124 | CHEMBL444501)
Affinity DataIC50:  2.79E+5nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase using ABTS as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591780(CHEMBL5171038)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591781(CHEMBL5203954)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591782(CHEMBL5181100)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591783(CHEMBL5177258)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591784(CHEMBL5196120)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591785(CHEMBL5176647)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591786(CHEMBL5207696)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591787(CHEMBL5198713)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591788(CHEMBL5174139)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591789(CHEMBL5208477)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591790(CHEMBL5171832)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591791(CHEMBL5185818)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591792(CHEMBL5201236)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591793(CHEMBL5186398)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591794(CHEMBL5191977)
Affinity DataEC50:  9.72E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50292579(CHEMBL459826 | Peucedanone)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591773(CHEMBL5182080)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591772(CHEMBL5207605)
Affinity DataEC50:  1.59E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591771(CHEMBL5195163)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591770(CHEMBL5179804)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591769(CHEMBL5200407)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591779(CHEMBL5191516)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591778(CHEMBL5176175)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591777(CHEMBL5196422)
Affinity DataEC50:  1.87E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591774(CHEMBL5203645)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591775(CHEMBL5189977)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591776(CHEMBL5181220)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed