Affinity DataIC50: 3nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: <14nM EC50: 2.20E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,M2833T,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 19nM EC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nM EC50: 7.10E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of HCV BK NS5B deltaC55 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 30nM EC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelationMore data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome
Irbm, Mrl Rome
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 42nM EC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against HCV 2a BK NS5B deltaC21 RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant C-terminally flag tagged HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of C-terminal FLAG tagged HDAC1 (unknown origin)More data for this Ligand-Target Pair