Found 195 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM19149' 
Affinity DataKi: 173nMAssay Description:Competitive inhibition of HDAC8 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 396nMAssay Description:Inhibition of human recombinant HDAC8 using fluorescent acetylated substrateMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:The compound was tested in vitro for binding activity against M1 muscarinic receptor in homogenates of the cerebral cortex of rat using [3H]pirenzepi...More data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of human recombinant HDAC8 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of human recombinant HDAC8 using [Ac-Leu-Gly-Lys(Ac)-AMC substrate incubated for 15 to 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nM ΔG°: -32.2kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Affinity DataKi: 5.33E+3nMAssay Description:Inhibition of recombinant human HDAC8More data for this Ligand-Target Pair
Affinity DataKi: 1.57E+4nMAssay Description:Inhibition of C-terminal His-fusion tagged/N-terminal Strep-2 tagged recombinant human HDAC8 (1 to 377 residues) expressed in insect cells using Boc-...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human recombinant HDAC8 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in sf9 insect cells using Boc-Lys(TFA)-AM as substrate incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of HDAC8 (unknown origin) measured after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC8 (unknown origin) by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Inhibition of HDAC8 (unknown origin) measured by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human HDAC8 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 188nMAssay Description:Inhibition of human recombinant HDAC8 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropla...More data for this Ligand-Target Pair
Affinity DataIC50: 192nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Ac-peptide-AMC as substrate incubated for 240 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of HDAC8 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of HDAC8 (unknown origin) after 60 mins by SAMDI spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of HDAC8 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacFGC as substrate after 60 mins by SAMDI mas...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of His-tagged HDAC8 (unknown origin) expressed in Escherichia coli BL21(DE3) after 60 mins by MALDI mass spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 232nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
Affinity DataIC50: 239nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys-(triflouroacetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC8 using AMC-K(Ac)GL as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC-8 using RHK(Ac)K(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC-8 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
