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Found 53 with Last Name = 'balestri' and Initial = 'f'
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  6.20nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  16nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi: >300nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi: >500nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataKi:  7.60E+3nMAssay Description:Mixed non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  1.20E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  1.20E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  1.31E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  1.31E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataKi:  4.06E+4nMAssay Description:Mixed non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506665(CHEMBL4554837)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149769((Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334182(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  102nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506664(CHEMBL4436037)
Affinity DataIC50:  104nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506668(CHEMBL1384494)
Affinity DataIC50:  125nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016231(CHEMBL3262477)
Affinity DataIC50:  139nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016232(CHEMBL3262476)
Affinity DataIC50:  194nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016230(CHEMBL3262478)
Affinity DataIC50:  228nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataIC50:  276nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506666(CHEMBL4455326)
Affinity DataIC50:  323nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506662(CHEMBL4483615)
Affinity DataIC50:  364nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50284960(CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] |...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237631(CHEMBL4104131)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237633(CHEMBL4090580)
Affinity DataIC50:  2.37E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237634(CHEMBL4062614)
Affinity DataIC50:  2.80E+4nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataIC50:  3.25E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237630(CHEMBL4086221)
Affinity DataIC50:  3.42E+4nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237632(CHEMBL4096393)
Affinity DataIC50:  4.23E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  4.31E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506664(CHEMBL4436037)
Affinity DataIC50:  4.94E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506665(CHEMBL4554837)
Affinity DataIC50:  5.41E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149769((Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  5.61E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506662(CHEMBL4483615)
Affinity DataIC50:  6.38E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237636(CHEMBL4078350)
Affinity DataIC50:  6.71E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237637(CHEMBL4101013)
Affinity DataIC50:  7.28E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  8.68E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50237635(CHEMBL4066446)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506666(CHEMBL4455326)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506668(CHEMBL1384494)
Affinity DataIC50:  1.71E+5nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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