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Found 38 with Last Name = 'ballekova' and Initial = 'j'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataKi:  17nMAssay Description:Uncompetitive inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldeh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataKi:  66nMAssay Description:Uncompetitive inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50:  13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50:  13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50:  13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50:  13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50:  20nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50:  21nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50:  58nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50:  58nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50:  84nMAssay Description:Inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451730(CHEMBL4207775)
Affinity DataIC50:  169nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  227nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451733(CHEMBL1897400)
Affinity DataIC50:  340nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50:  4.84E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50:  9.43E+3nMAssay Description:Inhibition of recombinant human AKR1B10More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50:  9.98E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451730(CHEMBL4207775)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451733(CHEMBL1897400)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237631(CHEMBL4104131)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237633(CHEMBL4090580)
Affinity DataIC50:  2.37E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237634(CHEMBL4062614)
Affinity DataIC50:  2.80E+4nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237630(CHEMBL4086221)
Affinity DataIC50:  3.42E+4nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50:  3.43E+4nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237632(CHEMBL4096393)
Affinity DataIC50:  4.23E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50:  4.38E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  5.61E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  5.61E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237636(CHEMBL4078350)
Affinity DataIC50:  6.71E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237637(CHEMBL4101013)
Affinity DataIC50:  7.28E+4nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237635(CHEMBL4066446)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Wistar rat kidney ALR1 assessed as reduction in NADPH oxidation using D-glycuronate as substrate by UV-visible spectrophotometric metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Slovak Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed