Affinity DataKi: 0.0500nMAssay Description:Inhibition of human MMP-2 assessed as inhibition constant using MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibition of human MMP-12 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of human MMP-9 assessed as inhibition constant using MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Inhibition of MMP-9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
West China Hospital
Curated by ChEMBL
West China Hospital
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to EZH2 mutant (unknown origin) assessed as apparent inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
West China Hospital
Curated by ChEMBL
West China Hospital
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to wild-type EZH2 (unknown origin) assessed as apparent inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human recombinant HDAC3 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of MMP-12 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition of human MMP-12 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 11.9nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 12.8nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 13.1nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 13.1nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 13.7nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 18.2nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
TargetProstate-specific antigen(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 18.6nMAssay Description:Inhibition of prostate-specific antigen assessed as substrate hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human MMP-12 expressed in Escherichia coli BL21(DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair