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Found 24 with Last Name = 'barbieri' and Initial = 'a'
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006246(CHEMBL56734 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  90nMAssay Description:Binding affinity of the compound to m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006245(CHEMBL59587 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  140nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006243(((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...)
Affinity DataKi:  490nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006246(CHEMBL56734 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  690nMAssay Description:Binding affinity of the compound to m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006246(CHEMBL56734 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity of the compound to m-AcChR subtype M1 of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006245(CHEMBL59587 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006245(CHEMBL59587 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  2.94E+3nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006247(CHEMBL59085 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006244(CHEMBL294470 | Trimethyl-(5-methyl-4-oxo-tetrahydr...)
Affinity DataKi:  5.64E+3nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006244(CHEMBL294470 | Trimethyl-(5-methyl-4-oxo-tetrahydr...)
Affinity DataKi:  9.55E+3nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006243(((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M1 of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006244(CHEMBL294470 | Trimethyl-(5-methyl-4-oxo-tetrahydr...)
Affinity DataKi:  1.86E+4nMAssay Description:Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006247(CHEMBL59085 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  2.12E+4nMAssay Description:Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006243(((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...)
Affinity DataKi:  2.16E+4nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M2 of rat heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006247(CHEMBL59085 | Trimethyl-(5-methyl-4-oxo-tetrahydro...)
Affinity DataKi:  4.20E+4nMAssay Description:Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006248((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...)
Affinity DataKi:  1.04E+5nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M3 of rat sabmandibular glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006248((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...)
Affinity DataKi:  2.20E+5nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M1 of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Istituto Chimico-Farmaceutico Dell'Università

Curated by ChEMBL
LigandPNGBDBM50006248((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...)
Affinity DataKi:  2.52E+5nMAssay Description:Binding affinity of the compound against muscarinic acetylcholine receptor M2 of rat heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  25nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM50179009(CHEMBL377937 | Kuwanon L)
Affinity DataIC50:  570nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris·HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM50179009(CHEMBL377937 | Kuwanon L)
Affinity DataIC50:  990nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM189342(RDS1759)
Affinity DataIC50:  7.40E+3nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris·HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM189342(RDS1759)
Affinity DataIC50: >5.00E+4nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University of Siena

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50: >5.00E+4nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris·HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair