Compile Data Set for Download or QSAR
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Found 5 with Last Name = 'barnes' and Initial = 'kr'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262097(1-((5-acetoxy-11-hydroxy-4-(methoxymethyl)-4a,6a-d...)
Affinity DataIC50:  68nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262095((Z)-6-(((5-acetoxy-11-hydroxy-4-(methoxymethyl)-4a...)
Affinity DataIC50:  108nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262139(2-acetamido-6-((5-acetoxy-11-hydroxy-4-(methoxymet...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM68273(WmC20-cys, 3)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed