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Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50262097'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262097(1-((5-acetoxy-11-hydroxy-4-(methoxymethyl)-4a,6a-d...)
Affinity DataIC50:  68nMAssay Description:Inhibition of PI3 kinase by WmC20 derivatives causing a formation of covalent bond between WmC20 derivatives and the target protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262097(1-((5-acetoxy-11-hydroxy-4-(methoxymethyl)-4a,6a-d...)
Affinity DataIC50:  68nMAssay Description:Inhibition of PI3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Massachusetts General Hospital

LigandPNGBDBM50262097(1-((5-acetoxy-11-hydroxy-4-(methoxymethyl)-4a,6a-d...)
Affinity DataIC50:  105nMAssay Description:Inhibition of PI3K (unknown origin) by fluorescence energy transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed