Affinity DataKi: 0.190nM ΔG°: -54.9kJ/mole EC50: 0.660nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.299nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 0.543nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 0.998nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 1.54nM ΔG°: -49.8kJ/mole EC50: 3.61nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]-TTNPB from RARalpha/RXRalpha (unknown origin) expressed in baculovirus expression system by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...More data for this Ligand-Target Pair
Affinity DataKi: 2.68nM ΔG°: -48.4kJ/mole EC50: 19.4nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-TTNPB from RARalpha/RXRalpha (unknown origin) expressed in baculovirus expression system by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]-methyltrienolone from human androgen receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]-TTNPB from RARalpha/RXRalpha (unknown origin) expressed in baculovirus expression system by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]-TTNPB from RARalpha/RXRalpha (unknown origin) expressed in baculovirus expression system by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 14.5nM ΔG°: -44.3kJ/mole EC50: 32.5nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to human N-myristoyltransferase by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human leukocyte elastase by substrate hydrolysis based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human NMT1 by 7-diethylamine-3-(4'maleimidylphenyl)-4-methylcoumarin based fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of human NMT1 using GSNKSKPKDASQRRR-NH2 as substrate by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of human leukocyte elastase by substrate hydrolysis based fluorescence assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-aldosterone from human mineralocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competit...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]-progesterone from human progesterone receptor expressed in HEK293 cells by scintillation counting based radioligand competition ...More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Binding affinity to human N-myristoyltransferase by fluorescence analysisMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair