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Found 299 with Last Name = 'barrett' and Initial = 'v'
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  0.501nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  3nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473516(CHEMBL2110299)
Affinity DataIC50:  3.60nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataIC50:  6.20nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473505(CHEMBL2368256)
Affinity DataIC50:  7.10nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473521(CHEMBL159332 | CP-122288)
Affinity DataIC50:  7.20nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473512(CHEMBL2368254)
Affinity DataIC50:  9.5nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473521(CHEMBL159332 | CP-122288)
Affinity DataIC50:  14nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473512(CHEMBL2368254)
Affinity DataIC50:  14nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473508(CHEMBL158638)
Affinity DataIC50:  15nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  15.8nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473516(CHEMBL2110299)
Affinity DataIC50:  18nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(CHEMBL245568 | SB-649701)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(CHEMBL245568 | SB-649701)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473504(CHEMBL3084967)
Affinity DataIC50:  29nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473505(CHEMBL2368256)
Affinity DataIC50:  32nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423251(CHEMBL240461)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423244(CHEMBL397395)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473508(CHEMBL158638)
Affinity DataIC50:  45nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423250(CHEMBL395424)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473509(CHEMBL2368257)
Affinity DataIC50:  57.5nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473509(CHEMBL2368257)
Affinity DataIC50:  58nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473501(CHEMBL2368253)
Affinity DataIC50:  65nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  89nMAssay Description:Binding affinity against calf caudate 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473509(CHEMBL2368257)
Affinity DataIC50:  97.7nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473501(CHEMBL2368253)
Affinity DataIC50:  98nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473509(CHEMBL2368257)
Affinity DataIC50:  98nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  100nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(CHEMBL245568 | SB-649701)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in Th2 cells assessed as I309 mediated migration by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  100nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  112nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423259(CHEMBL395211)
Affinity DataIC50:  126nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473502(CHEMBL159470)
Affinity DataIC50:  141nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473504(CHEMBL3084967)
Affinity DataIC50:  141nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  162nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  162nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473520(CHEMBL2368259)
Affinity DataIC50:  191nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473510(CHEMBL2368261)
Affinity DataIC50:  195nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473510(CHEMBL2368261)
Affinity DataIC50:  204nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423248(CHEMBL247965)
Affinity DataIC50:  251nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473513(CHEMBL350277)
Affinity DataIC50:  263nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473520(CHEMBL2368259)
Affinity DataIC50:  275nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473502(CHEMBL159470)
Affinity DataIC50:  316nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473513(CHEMBL350277)
Affinity DataIC50:  339nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473503(CHEMBL2110300)
Affinity DataIC50:  363nMAssay Description:Binding affinity towards human recombinant 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423256(CHEMBL443315)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473515(CHEMBL2368255)
Affinity DataIC50:  501nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50423246(CHEMBL245568 | SB-649701)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at human recombinant CCR8 expressed in HUT78 cells assessed as I309-mediated migration by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50473519(CHEMBL350637)
Affinity DataIC50:  562nMAssay Description:Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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