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Found 32 with Last Name = 'barteau' and Initial = 's'
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50:  120nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50:  220nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50:  3.14E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50:  3.46E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50:  8.91E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50:  9.88E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as S-mephenytoin 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as S-mephenytoin 4'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as S-mephenytoin 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as bupropion hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438846(CHEMBL2413881)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as chlorzoxazone 6-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as bupropion hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as chlorzoxazone 6-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as bupropion hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as bupropion hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as chlorzoxazone 6-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as chlorzoxazone 6-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as S-mephenytoin 4'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444546(CHEMBL2414256)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50444547(CHEMBL3099819)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed