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Found 525 with Last Name = 'bastos' and Initial = 'c'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120351(US8703811, 93)
Affinity DataIC50:  35nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120317(US8703811, 58)
Affinity DataIC50:  36nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120319(US8703811, 60)
Affinity DataIC50:  38nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120301(US8703811, 40 | US8703811, 41)
Affinity DataIC50:  40nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Genzyme

US Patent
LigandPNGBDBM92606(DHOD Inhibitor, 5 | US8703811, 6)
Affinity DataIC50:  40nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120323(US8703811, 64)
Affinity DataIC50:  41nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)
Affinity DataIC50:  42nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent
LigandPNGBDBM120324(US8703811, 65)
Affinity DataIC50:  42nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590227(US11560385, Compound 3B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590228(US11560385, Compound 4B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590230(US11560385, Compound 6B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590231(US11560385, Compound 7B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590232(US11560385, Compound 8B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590233(US11560385, Compound 9B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590234(US11560385, Compound 10B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590236(US11560385, Compound 12B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590237(US11560385, Compound 13B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590238(US11560385, Compound 14B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590239(US11560385, Compound 15B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590244(US11560385, Compound 20B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590246(US11560385, Compound 22B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590247(US11560385, Compound 23B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590250(US11560385, Compound 26B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590251(US11560385, Compound 27B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590253(US11560385, Compound 28B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590254(US11560385, Compound 29B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590255(US11560385, Compound 30B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590261(US11560385, Compound 34B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590262(US11560385, Compound 35B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590263(US11560385, Compound 37B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590265(US11560385, Compound 38B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590266(US11560385, Compound 39B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590267(US11560385, Compound 40B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590268(US11560385, Compound 41B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590269(US11560385, Compound 42B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590270(US11560385, Compound 43B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590271(US11560385, Compound 44B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590272(US11560385, Compound 45B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590274(US11560385, Compound 47B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590276(US11560385, Compound 51B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590277(US11560385, Compound 52B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590278(US11560385, Compound 53B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590279(US11560385, Compound 54B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590280(US11560385, Compound 55B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590299(US11560385, Compound 80B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590711(US11560385, Compound 153B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590713(US11560385, Compound 156B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590309(US11560385, Compound 90B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590327(US11560385, Compound 108B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590680(US11560385, Compound 120B)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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