Affinity DataIC50: <1nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 223nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Rutgers University
Curated by ChEMBL
Rutgers University
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Inhibition of HIV-1 reverse transcriptase E138K mutant-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Rutgers University
Curated by ChEMBL
Rutgers University
Curated by ChEMBL
Affinity DataIC50: 244nMAssay Description:Inhibition of HIV-1 reverse transcriptase K101E mutant-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 2.00E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 3.30E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of wild type HIV-1 reverse transcriptase-mediated polymerization reaction after 30 minsMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 4.70E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 7.40E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 7.60E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 1.06E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 1.08E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 1.22E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 1.32E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 2.40E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair