Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.776nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.813nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosolMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1A expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair