TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibitory activity against protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Inhibitory activity against protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 560nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 830nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 860nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibitory constant against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibitory activity against SH-domain containing phosphotyrosine phosphatase-2 (Tyrosine phosphatase SHP2) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibitory activity against CD45 tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibitory activity against cell division cycle 25 degree C (Cdc25 C) was determinedMore data for this Ligand-Target Pair
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Inhibitory activity against (calcineurin) was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 9.60E+4nMAssay Description:Inhibitory activity against SH-domain containing phosphotyrosine phosphatase-2 (Tyrosine phosphatase SHP2) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.78E+5nMAssay Description:Inhibitory activity against Cell division cycle 25 degree C was determinedMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity against CD45 tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity against (calcineurin) was determinedMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 7.20E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 9.90E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 9.00E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.16E+5nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.70E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 7.70E+4nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.07E+5nMAssay Description:Displacement of [125I]GVIA from Cav2.2 channel in rat brain by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 1.56E+7nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 1.20E+6nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 9.10E+5nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair