Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM48319'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Protein-tyrosine phosphatase 1B (PTP 1B) site 2 Ligands were identified using [13C]-labeled protein and their Dissociation Constants were determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+6nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+3nMAssay Description:Dissociation constant of the compound against protein tyrosine phosphatase PTB1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed